ERA, or Endometrial Receptivity Analysis, is a test to determine the receptivity of the endometrium.
ERA may increase the chance of pregnancy by predicting the ideal time for the implantation of the embryo during an IVF cycle.
A biopsy of endometrial tissue is taken and analyzed. Results will indicate whether the endometrium was receptive or non-receptive at the time the biopsy was taken.
A receptive result indicates the endometrium is likely to be receptive and the embryo is likely capable of implanting into the uterus relative to the day the biopsy was taken.
A non-receptive result indicates that the endometrium is either pre- or post-receptive relative to the day that the biopsy was taken. The embryo transfer would not be recommended.
A non-receptive result means the endometrium is either pre-receptive or post-receptive.
In this case, a new window of implantation will be suggested and a second biopsy and test are recommended to confirm the new personalized window of implantation.
ERA links to a major improvement of the global pregnancy rate, up to 85%* in those personalized transfers made according to the test results.
* SREI Prize Paper. O-115 Simón et al. on behalf of the ERA RCT Consortium. Prospective, randomized study of the Endometrial Receptivity Analysis (ERA) test in the infertility work-up to guide personalized embryo transfer versus fresh transfer or deferred embryo transfer.